Anti-Human/Mouse IRF5 Monoclonal Antibody

IRF5,also named as SLEB10,contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10).
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02016
Size 100μl
Host Type Mouse
Immunogen Fusion protein of IRF5
Specificity
Isotype IgG2a
Reacitivity Human,Mouse
Clone 650
Uniprot Q13568
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names Interferon regulatory factor 5,Interferon regulatory factor 5 bone marrow variant,IRF 5,IRF-5,Irf5,IRF5,SLEB10
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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