Anti-Human/Mouse CD305 Polyclonal Antibody

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12400
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human LAIR1
Specificity Expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells. Highly expressed in naive T-cells and B-cells but no expression on germinal center B-cells. Abnormally low expression in naive B-cells from HIV-1 infected patients. Very low expression in NK cells from a patient with chronic active Epstein-Barr virus infection.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q6GTX8
Concentration 0.2 mg/mL
Dilution WB 1:500-1:2000, IHC 1:15-1:50
Formulation
Application WB,IHC,ELISA
Other Names 5133400O11Rik,CD305,D7Bwg0421e,hLAIR1,LAIR 1,LAIR-1,LAIR1,LAIR1 protein,LAIR1,Leukocyte associated Ig like receptor 1,Leukocyte associated immunoglobulin like receptor 1,Leukocyte-associated immunoglobulin-like receptor 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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