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Anti-Human/Mouse CABLES1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02377
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Cables1
Specificity Expressed in breast, pancreas, colon, head and neck (at protein level). Strongly decreased in more than half of cases of atypical endometrial hyperplasia and in more than 90% of endometrial cancers.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8TDN4
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names CABL1,CABLES,Cables1,Cdk5 and Abl enzyme substrate 1,CDK5 and ABL1 enzyme substrate 1,FLJ35924,HsT2563,IK3 1,Ik3-1,Interactor with CDK3 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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