Anti-Human/Mouse BIRC2 Polyclonal Antibody

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12749
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human BIRC2
Specificity Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q13490
Concentration 0.1 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names API 1,API1,Apoptosis inhibitor 1,Baculoviral IAP repeat containing 2,Baculoviral IAP repeat containing protein 2,Baculoviral IAP repeat-containing protein 2,BIRC 2,BIRC2,BIRC2,C IAP1,C-IAP1,cIAP 1,cIAP1,HIAP 2,HIAP-2,HIAP2,IAP 2,IAP homolog B,IAP-2,IAP2,Inhibitor of apoptosis protein 2,MIHB,NFR2 TRAF signalling complex protein,RING finger protein 48,RNF 48,RNF48,TNFR2 TRAF signaling complex protein 2,TNFR2-TRAF-signaling complex protein 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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