Home / Products / antibodies / Anti-Human/Monkey Phospho-PGR (Ser190) Polyclonal Antibody

Anti-Human/Monkey Phospho-PGR (Ser190) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
List Price: $398
  • Buy 5 for $378.1 each and save 5%
  • Buy 21 for $358.2 each and save 10%
  • Buy 31 for $338.3 each and save 15%
  • Buy 51 for

Properties

Data Sheet Click for Datasheet
Catalog Number PA01622
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human PR around the phosphorylation site of Ser190
Specificity In reproductive tissues the expression of isoform A and isoform B varies as a consequence of developmental and hormonal status. Isoform A and isoform B are expressed in comparable levels in uterine glandular epithelium during the proliferative phase of the menstrual cycle. Expression of isoform B but not of isoform A persists in the glands during mid-secretory phase. In the stroma, isoform A is the predominant form throughout the cycle. Heterogeneous isoform expression between the glands of the endometrium basalis and functionalis is implying region-specific responses to hormonal stimuli.
Isotype IgG
Reacitivity Human,Monkey
Clone
Uniprot P06401
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
CONTACT US
How to order

Featured Products

© Copyright 2024 TZYBIOTECH. All Rights Reserved. SiteMap