Anti-Human LIN28A Monoclonal Antibody

LIN28 is one of the four key human factors (OCT4,SOX2,NANOG and LIN28) used to reprogram human fibroblasts to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (Ips) cell. Lin28 is a marker of undifferentiated human embryonic stem cells and a cytoplasmic Mrna-binding protein that binds to and enhances the translation of the IGF2 Mrna. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02026
Size 100μl
Host Type Mouse
Immunogen Fusion protein of LIN28
Specificity Expressed in embryonic stem cells (ES cells), placenta and testis.
Isotype IgG1
Reacitivity Human
Clone 8700
Uniprot Q9H9Z2
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names AL024421,CSDD1,CSDD2,FLJ12457,Lin 28,Lin 28 homolog (C. elegans),Lin 28 homolog A (C. elegans),Lin 28 homolog A,Lin 28 homolog,Lin-28A,Lin28,Lin28,C. elegans,homolog of,A,LIN28A,LN28A,Protein lin-28 homolog A,Protein lin-28 homolog B,RNA binding protein lin 28,Tex17,ZCCHC1,Zinc finger CCHC domain containing 1,Zinc finger CCHC domain containing protein 1,Zinc finger CCHC domain-containing protein 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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