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Anti-Human LDLR Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02500
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of LDLR
Specificity
Isotype IgG1
Reacitivity Human
Clone 1A2A3
Uniprot P01130
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names FH,FHC,LDL R,LDL receptor,LDLCQ2,Ldlr,LDLR,Low Density Lipoprotein Receptor,Low density lipoprotein receptor class A domain containing protein 3,Low density lipoprotein receptor familial hypercholesterolemia,Low-density lipoprotein receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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