Anti-Human KNG1 Monoclonal Antibody

Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This gene is translated into High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) after alternative splicing. HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation,and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues,and secreted together with tissue kallikrein.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02020
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Kininogen 1
Specificity Secreted in plasma. T-kinin is detected in malignant ovarian, colon and breast carcinomas, but not in benign tumors.
Isotype IgG1
Reacitivity Human
Clone 834
Uniprot P01042
Concentration None
Dilution WB 1:5000-1:20000, IHC 1:20-1:200, IF 1:50-1:500
Formulation
Application WB,IHC,IF,ELISA
Other Names Alpha-2-thiol proteinase inhibitor,BDK,BK,Fitzgerald factor,High molecular weight kininogen,HMWK,Ile-Ser-Bradykinin,Kallidin I,Kallidin II,Kininogen 1,KNG,KNG1,KNG1,LMW,Low molecular weight growth-promoting factor,Low molecular weight kininogen,Williams-Fitzgerald-Flaujeac factor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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