Anti-Human IL22RA2 Monoclonal Antibody

Interleukin-22 receptor subunit alpha-2 (IL22RA2) is a soluble member of the type II cytokine receptor family. Through binding to IL22,IL22RA2 prevents the interaction of IL22 with the functional IL22-R complex and blocks the activity of IL22 (in vitro). IL22RA2 may play an important role as an IL22 antagonist in the regulation of inflammatory responses. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02009
Size 100μl
Host Type Mouse
Immunogen Fusion protein of IL22RA2
Specificity Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
Isotype IgG2a
Reacitivity Human
Clone 456
Uniprot Q969J5
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names IL 22BP, IL 22RA2, IL22RA2,Class II cytokine receptor,CRF2 10,CRF2 S1,CRF2-10,CRF2-S1,CRF2X,Cytokine receptor class II member 10,Cytokine receptor class-II member 10,Cytokine receptor family 2 member 10,Cytokine receptor family type 2,Cytokine receptor family type 2 soluble 1,I22R2,IL 22 receptor subunit alpha 2,IL 22R alpha 2,IL-22 receptor subunit alpha-2,IL-22BP,IL-22R-alpha-2,IL-22RA2,IL22BP,IL22R alpha 2,Il22ra2,Interleukin 22 binding protein,Interleukin 22 Receptor alpha 2,Interleukin-22 receptor subunit alpha-2,Interleukin-22-binding protein,MGC150509,MGC150510,soluble 1,ZcytoR16
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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