Anti-Human IDS Monoclonal Antibody

Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome,an X chromosome-linked disease. An internal proteolytic cleavage occurs to produce the mature IDS present in human liver shown to contain a 42 kDa polypeptide N-terminal to a 14 kDa polypeptide..
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01999
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Iduronate 2 sulfatase
Specificity Liver, kidney, lung, and placenta.
Isotype IgG1
Reacitivity Human
Clone 3210
Uniprot P22304
Concentration None
Dilution WB 1:200-1:2000, IHC 1:20-1:200, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names Alpha L iduronate sulfate sulfatase,Alpha-L-iduronate sulfate sulfatase,AW214631,Ids,IDS,Iduronate 2 sulfatase 14 kDa chain,Iduronate 2 sulfatase 42 kDa chain,Iduronate 2 sulfatase,Iduronate 2-sulfatase 14 kDa chain,Iduronate sulfatase,Idursulfase,MPS2,RP23-29M4.1,SIDS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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