Anti-Human GSN Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]

Gelsolin (GSN) is an actin binding protein that regulates actin-severing/depolymerizing in a calcium dependent manner,and acts as a multifunctional regulator for cell metabolism and survival. Gelsolin exists in two isoforms: a cytoplasmic gelsolin (cGSN; 80-90 kDa) and a plasma gelsolin (pGSN; 93 kDa),differing at N terminal residues. Decreased levels of pGSN are strongly associated with human diseases,such as,acute liver injury,major trauma,myocardial infarction,inflammation,lung injury,rheumatoid arthritis,hemodialysis,multiple sclerosis,Alzheimer's disease.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01984
Size	100μl
Host Type	Mouse
Immunogen	Fusion protein of Gelsolin
Specificity	Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.
Isotype	IgA
Reacitivity	Human
Clone	134
Uniprot	P06396
Concentration	None
Dilution	WB 1:1000-1:10000, IHC 1:20-1:1000
Formulation
Application	WB,IHC,ELISA
Other Names	Actin depolymerizing factor,Actin-depolymerizing factor,ADF,AGEL,Brevin,DKFZp313L0718,GELS,Gelsolin,Gsn
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human GSN Monoclonal Antibody

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