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Anti-Human EPCAM Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Epithelial cell adhesion molecule (EpCAM,CD326) is a type I transmembrane glycoprotein that functions as a homophilic,epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion,EpCAM is also involved in cellular signaling,cell migration,proliferation,and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas,and has become a therapeutic target.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02471
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of EPCAM
Specificity Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
Isotype IgG2a
Reacitivity Human
Clone 2A2D5
Uniprot P16422
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:50-1:500, IF 1:50-1:500
Formulation
Application WB,IHC,IF,ELISA
Other Names 17 1A,323/A3,Adenocarcinoma associated antigen,Adenocarcinoma-associated antigen,Antigen identified by monoclonal AUA1,AUA1,CD326,CD326 antigen,Cell surface glycoprotein Trop 1,Cell surface glycoprotein Trop 2,Cell surface glycoprotein Trop-1,CO 17A,CO17 1A,CO17A,DIAR5,EGP 2,EGP,EGP2,EGP314,EGP40,Ep CAM,Ep-CAM,EPCAM,EPCAM,EpCAM1,Epithelial cell adhesion molecule,Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD),Epithelial cell surface antigen,Epithelial cellular adhesion molecule,Epithelial glycoprotein 1,Epithelial glycoprotein 314,Epithelial glycoprotein,ESA,GA733 1,GA733 2,GA733-2,gastrointestinal tumor-associated antigen 2,35-KD glycoprotein,gp4,hEGP 2,hEGP314,HNPCC8,Human epithelial glycoprotein 2,KS 1/4 antigen,KS1/4,KSA,Ly74,Lymphocyte antigen 74,M1S 1,M1S2,M4S1,Major gastrointestinal tumor associated protein GA733 2,Major gastrointestinal tumor-associated protein GA733-2,mEGP314,Membrane component chromosome 4 surface marker (35kD glycoprotein),Membrane component,chromosome 4,surface marker 1,Membrane component,chromosome 4,surface marker,MIC18,MK 1,Protein 289A,TACD1,TACSTD1,TROP1,Tumor associated calcium signal transducer 1,Tumor associated calcium signal transducer 2 precursor,Tumor-associated calcium signal transducer 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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