Anti-Human DCLRE1B Polyclonal Antibody

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links.DCLRE1B (DNA Cross-Link Repair 1B) is a Protein Coding gene. Diseases associated with DCLRE1B include Fanconi Anemia, Complementation Group A and Dyskeratosis Congenita. Among its related pathways are Fanconi anemia pathway and DNA Double-Strand Break Repair. GO annotations related to this gene include 5-3 exonuclease activity. An important paralog of this gene is DCLRE1C.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06228
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human SNM1B.
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9H816
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names DCLRE1B,SNM1B,5' exonuclease Apollo,DNA cross-link repair 1B protein,SNM1 homolog B,SNMIB,hSNM1B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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