Anti-Human CERS3 Polyclonal Antibody

LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10304
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CERS3
Specificity Expressed in the epidermis, where it localizes at the interface between the stratum granulosum and the stratum corneum (at protein level).1 Publication
Isotype IgG
Reacitivity Human
Clone
Uniprot Q8IU89
Concentration 0.4 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names Ceramide synthase 3,CerS3,CERS3,LAG1 homolog,ceramide synthase 3,LAG1 longevity assurance homolog 3,LASS 3,MGC 27091
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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