Anti-Human CERKL Polyclonal Antibody

This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09504
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CERKL
Specificity Isoform 1 and isoform 2 are expressed in adult retina, liver and pancreas as well as in fetal brain, lung and kidney. Isoform 3 is expressed in adult retina as well as in fetal lung and liver. Isoform 4 is expressed in adult retina, lung and kidney as well as in fetal lung and liver. Moderately expressed in retina, kidney, lung, testis, trachea, and pancreas. Weakly expressed in brain, placenta and liver.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q49MI3
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Ceramide kinase like protein,Ceramide kinase-like protein,CERKL,CERKL,Retinitis pigmentosa 26 (autosomal recessive),RP26
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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