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Anti-Human CD27 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells,and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity . It is a receptor for CD70 (Cd27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways,as well as the JNK pathway . CD27 may also play a role in apoptosis through association with SIVA1.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02203
Size 100μl
Host Type Mouse
Immunogen Fusion protein of CD27
Specificity Found in most T-lymphocytes.
Isotype IgG1
Reacitivity Human
Clone 58
Uniprot P26842
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names CD 27,CD27,CD27 antigen,CD27 molecule,CD27,CD27L receptor,LPFS2,MGC20393,OTTHUMP00000238557,S152,T cell activation antigen CD27,T cell antivation antigen S152,T-cell activation antigen CD27,T14,TNFRSF 7,TNFRSF7,TNFSF7,Tp 55,Tp55,Tumor necrosis factor receptor superfamily member 7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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