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Recombinant Human TLK1 / PKU-beta Protein (His & GST tag)

Categories: [Proteins / Peptides]
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP08357
Size 20ug,50ug,100ug…
Host Baculovirus-Insect Cells
Accession Q9UKI8-1
Molecular Weight 114 kDa
AP_Mol_Weight 125 kDa
Tag N-His & GST
Sequences Met 1-Tyr 766
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names KIAA0137;PKU-beta
Bioactivity The specific activity was determined to be 1.6 nmol/min/mg using Histone H3 protein as substrate.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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