SNRPE, 1-92aa, Human, His tag, E.coli

SNRPE, also known as SME, aids in the cytoplasmic construction of the UsnRNPs by binding to a conserved Sm site on UsnRNA and forming a stable snRNP core complex. As a core protein to UsnRNP, the SNRPE associates with the entire U family of snRNAs including U1-U6. SNRPE also interacts with DDX20 and Small nuclear ribonucleoprotein polypeptide F. Recombinant human SNRPE protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.