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Rspo1, 21-265aa, Mouse, His-tag, Baculovirus

Categories: [Proteins / Peptides]
Rspo1, as known as R-spondin-1, is a member of the Rspondin family. It is an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors and in non-canonical Wnt signaling pathway by acting as an inhibitor of ZNRF3. Also, this protein induces the rapid onset of crypt cell proliferation and increses intestinal epithelial healing effect. Recombinant mouse Rspo1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP03806
Size 20 µg
Host Baculovirus
Accession
Molecular Weight 28.2kDa (254aa), 28-40kDa (SDS-PAGE under reducing conditions.)
AP_Mol_Weight
Tag
Sequences ADPSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCQEGLYLHKGRCYPACPEGSTAANSTMECGSPAQCEMSEWSPWGPCSKKRKLCGFRKGSEERTRRVLHAPGGDHTTCSDTKETRKCTVRRTPCPEGQKRRKGGQGRRENANRHPARKNSKEPGSNSRRHKGQQQPQPGTTGPLTSVGPTWAQHHHHHH
Purity > 95% by HPLC
Concentration 0.5mg/ml (determined by Absorbance at 280nm)
Formulation Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Other Names R-spondin-1, Rspo1, RSPO, R-spondin 1, R-spondin, Rspondin, CRISTIN3
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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