RGS17, 1-210aa, Human, His tag, E.coli

RGS17, also known as regulator of G-protein signaling 17, attenuates the signaling activity of Gproteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.