PKNOX1, 1-436, Human, His tag, E.coli

Hmeobox protein PKNOX1 is a DNA-binding protein that forms stable complexes with PBX proteins which synergize with AP-1 binding factors to augment transcription of the urokinase gene. Also referred to as UEF3, PRP-1 or p64, PKNOX1 appears to be a general DNA-binding factor involved in modulating the transcriptional activity of AP-1 containing promoters. Recombinant human PKNOX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.