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PIN4, 1-156aa, Human, His tag, E.coli

Categories: [Proteins / Peptides]
PIN4, also known as Peptidyl cis-trans isomerase NIMA-interacting 4, is peptidyl prolyl cis/trans isomerase (PPIase) that interacts with NIMA and is essential for cell cycle regulation. There are two different isoforms which are PAR14 and PAR17. PIN4/PAR17 was imported into mitochondria in a time and membrane potential dependent manner, where it reached the mitochondrial matrix.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP03411
Size 100 µg
Host E.coli
Accession
Molecular Weight 18.8 kDa (176aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
Sequences MGSSHHHHHHSSGLVPRGSHMPMAGLLKGLVRQLERFSVQQQASKMPPKGKSGSGKAGKGGAASGSDSADKKAQGPKGGGNAVKVRHILCEKHGKIMEAMEKLKSGMRFNEVAAQYSEDKARQGGDLGWMTRGSMVGPFQEAAFALPVSGMDKPVFTDPPVKTKFGYHIIMVEGRKtmp/IBATGP0999
Purity > 95% by HPLC
Concentration 1 mg/ml (determined by Bradford assay)
Formulation Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT, 0.1mM PMSF.
Other Names Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 isofom 2, Parvulin-14, Parvulin-17, PPIase Pin4, hEPVH, PAR14, PAR17.
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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