PDE6D, 1-150aa, Human, His tag, E.coli

Human PDE6D was originally identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. Catalytically active PDE6 is a heterodimer (αβ) that is regulated by two inhibitory γ subunits. As PDE6D does not modify the catalytic properties of PDEαβ, its function is still unresolved. Recombinant human PDE6D, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.