NFKBIA, 1-317aa, Human, His tag, E.coli

NF-kappa-B inhibitor alpha, also known as NFKBIA, is members of the IκB family of proteins can be divided into four groups (IκB-α, IκB-β, IκB-γ, IκB-ε). NFKBIA inhibits the NFκB complex by binding and sequestering it in the cytoplasm. Upon stimulation, NFKBIA is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	TP03148
Size	50 µg
Host	E.coli
Accession
Molecular Weight	37.7 kDa (337aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag	N-6His
Sequences	MGSSHHHHHHSSGLVPRGSHMFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
Purity	> 95% by HPLC
Concentration	0.5 mg/ml (determined by Bradford assay)
Formulation	Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
Other Names	NF-kappa-B inhibitor alpha, IKBA, MAD-3, NFKBI.
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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NFKBIA, 1-317aa, Human, His tag, E.coli

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