MX1, 1-662aa, Human, His tag, E.coli

MX1 is a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. This protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Recombinant human MX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.