MIF, 1-115 aa, Human, Recombinant, E.coli

The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	TP02974
Size	100 µg
Host	E.coli
Accession
Molecular Weight	12 kDa (115 aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag
Sequences	MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
Purity	> 95% by HPLC
Concentration	1 mg/ml (determined by Bradford assay)
Formulation	Liquid. In 50 mM Tris-HCl buffer (pH 8.0) containing 0.5 mM DTT 10% glycerol
Other Names	Macrophage migration inhibitory factor, Glycosylation inhibiting factor (GIF), GLIF, MMIF
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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MIF, 1-115 aa, Human, Recombinant, E.coli

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