MAEA, 1-396aa, Human, His tag, E.coli

Macrophage erythroblast attacher isoform 1, also known as MAEA, is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, MAEA contains one CTLH domain and one LisH domain. MAEA can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, MAEA is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Recombinant human MAEA protein, fused to His-tag at N-terminus, was expressed in E.coli.