LAIR-1( Extracellular domain ; 22-125aa, human), Recombinant, E.coli

Categories: [Proteins / Peptides]
LAIR-1 is a glycoprotein(~32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1( 22-125aa) was overexpressed in E.coli, and purified by using conventional chromatography techniques.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP02773
Size 100 µg
Host E.coli
Accession
Molecular Weight 11.7 kDa (105 aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag
Sequences MQEEDLPRPSISAEPGTVIPLGSHVTFVCRGPVGVQTFRLERESRSTYNDTEDVSQASPSESEARFRIDSVSEGNAGPYRCIYYKPPKWSEQSDYLELLVKETSG
Purity > 95% by HPLC
Concentration 1 mg/ml (determined by Bradford assay)
Formulation Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 50 mM NaC l1 mM EDTA
Other Names Leukocyte-associated immunoglobulin-like receptor 1 isoform a, LAIR1, CD305
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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