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IPP-1, 1-171aa, Human, His-tagged, Recombinant, E.coli

Categories: [Proteins / Peptides]
Protein phosphatase inhibitor-1(IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B).
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Properties

Data Sheet Click for Datasheet
Catalog Number TP02684
Size 100 µg
Host E.coli
Accession
Molecular Weight 20kDa (179aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag
Sequences MEQDNSPRKIQFTVPLLEPHLDPEAAEQIRRRRPTPATLVLTSDQSSPEIDEDRIPNPHLKSTLAMSPRQRKKMTRITPTMKELQMMVEHHLGQQQQGEEPEGAAESTGTQESRPPGIPDTEVESRLGTSGTAKKTAECIPKTHERGSKEPSTKEPSTHIPPLDSKGANSVLEHHHHHH
Purity > 95% by HPLC
Concentration 1 mg/ml (determined by Bradford assay)
Formulation Liquid. In 50 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT,1 mM EDTA, 0.1 mM PMSF, 10% glycerol
Other Names Protein phosphatase inhibitor-1, IPP-1, I-1, PPI-1
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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