GTF2H5, 1-71aa Human, His tag, E.coli

GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

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Data Sheet	Click for Datasheet
Catalog Number	TP02371
Size	100 µg
Host	E.coli
Accession
Molecular Weight	10.4 kDa (94aa) confirmed by MALDI-TOF
AP_Mol_Weight
Tag	N-6His
Sequences	MGSSHHHHHHSSGLVPRGSHMGSMVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLTQK
Purity	> 95% by HPLC
Concentration	1.0 mg/ml (determined by Bradford assay)
Formulation	Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol
Other Names	General transcription factor IIH subunit 5, bA120J8.2, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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GTF2H5, 1-71aa Human, His tag, E.coli

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