Elongin B, 1-118aa, Human, Recombinant, E.coli

Elongin B , also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	TP02009
Size	100 µg
Host	E.coli
Accession
Molecular Weight	13.1 kDa (118 aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag
Sequences	DVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMKPQDSGSSANEQAVQ
Purity	> 95% by HPLC
Concentration	1 mg/ml (determined by Bradford assay)
Formulation	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mMDTT,0.1 mM PMSF, 20% glycerol
Other Names	Transcription elongation factor B polypeptide 2, TCEB2, RNA polymerase II transcription factor SIII subunit B, SIII p18, EloB, Elongin 18 kDa subunit
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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Elongin B, 1-118aa, Human, Recombinant, E.coli

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