CRADD Monoclonal Antibody (Clone AT14G8)

Chitinase 3-Like-1 (CHI3L1) is a recently discovered human glycoprotein which is related in amino acid sequence to the chitinase protein family, but has no chitinase activity. CHI3L1 is upregulated in a number of cancers and in non-neoplatic disease states characterized by chronic inflammation and tissue remodeling. Its pattern of expression is associated with pathogenic processes related to inflammation, extracellular tissue remodeling, fibrosis and solid carcinomas. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01196
Size 100 µL
Host Type Mouse
Immunogen Recombinant human CHI3L1 (22-383aa) purified from E. coli
Specificity
Isotype IgG2b,k
Reacitivity Human
Clone Anti-human CHI3L1 mAb, clone AT4D12, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CHI3L1 protein.
Uniprot
Concentration 1 mg/mL
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, ICC/IF
Other Names Chitinase 3-like 1, GP39, ASRT7, YKL40, YYL-40, HC-gp39, HCGP-3P.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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