AZGP1, also known as zinc-alpha-2-glycoprotein, is a member of the MHC class 1 family of proteins. It is reported to associate with PIP (prolactin-inducible protein) but not the MHC light chain, B 2-microglobulin. It is produced by secretory epithelia and is present in most body fluids. It stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. Recombinant human AZGP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.