TNFRSF17, also known as tumor necrosis factor receptor superfamily member 17, is a member of the TNF receptor superfamily. It is a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL and promotes B-cell survival and plays a role in the regulation of humoral immunity. It activates NF-kappa-B and JNK. Recombinant human TNFRSF17, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.