TCEAL1 (Transcription elongation factor A protein-like 1) is belongs to transcription elongation factor A (SII)-like (TCEAL) family. This family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. It involved in transcriptional regulation. This protein expressed in all tissues, especially highly expressed in heart, ovary, prostate and skeletal muscle. Recombinant human TCEAL1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.