Galectin-related protein, also known as LGALSL, is a 172 amino acid protein that contains one galectin domain. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. However, LGALSL does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. Recombinant human LGALSL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.