LAMP3, also known as lysosome-associated membrane glycoprotein 3, is a member of the lysosome-associated membrane protein family. LAMP3 and CD68 share very similar predicted structure. It may play a role in dendritic cell function and in adaptive immunity. Overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. Recombinant human LAMP3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.