IP6K2 also known as Inositol hexakisphosphate kinase 2, belongs to the inositol IPK family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Recombinant human IP6K2, fused to His-tag at N-terminus, was expressed in E.coli