Il17rb, 18-286aa, Mouse, hIgG-His-tag, Baculovirus

重组小鼠白介素17受体B

Il17rb, also known as Interleukin-17 receptor B, is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17(A) or IL17C. It has been shown to mediate the activation of NF- ?B and the production of IL8 induced by IL17E. It was found to be significantly up-regulated during intestinal inflammation, which suggested the immune regulatory activity of this receptor. Recombinant mouse Il17rb, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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基本信息

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货号 TP02617
规格 50 µg
宿主 Baculovirus
Accession
分子大小 57.1kDa (511aa), 57-70KDa (SDS-PAGE under reducing conditions.)
AP_Mol_Weight
Tag
蛋白序列 ADPREPTIQCGSETGPSPEWMVQHTLTPGDLRDLQVELVKTSVAAEEFSILMNISWILRADASIRLLKATKICVSGKNNMNSYSCVRCNYTEAFQSQTRPSGGKWTFSYVGFPVELSTLYLISAHNIPNANMNEDSPSLSVNFTSPGCLNHVMKYKKQCTEAGSLWDPDITACKKNEKMVEVNFTTNPLGNRYTILIQRDTTLGFSRVLENKLMRTSVAIPVTEESEGAVVQLTPYLHTCGNDCIRREGTVVLCSETSAPIPPDDNRRMLGGVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
纯度 > 95% by HPLC
浓度 1mg/ml (determined by Absorbance at 280nm)
配方 Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
别名 Interleukin-17 receptor B, Il17rb, Evi27, IL-17ER, IL-17Rh1, Il17br, IL17RH1
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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