IL-2 (Interleukin-2), also known as T cell growth factor(TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of Bcells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.