HMGB1, 1-215 aa, Human, His tagged, Recombinant, Baculovirus

重组人高迁移率族蛋白框1

High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor.
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基本信息

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货号 TP02468
规格 100 µg
宿主 Baculovirus
Accession
分子大小 25kDa (223aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
蛋白序列 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDELEHHHHHH
纯度 > 95% by HPLC
浓度 1 mg/ml (determined by Bradford assay)
配方 Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 0.5 mM DTT,1 mM EDTA, 10% glycerol
别名 High-mobility group box1, HMG1, HMG3, SBP-1
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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