GIPC Antibody (Clone AT1G10)

抗人GIPC单克隆抗体

GIPC, GAIP interacting protein at the C terminus, is a PDZ domain containing protein that interacts with RGS-GAIP. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.
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基本信息

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货号 MA01280
规格 100 µL
宿主 Mouse
免疫原 Recombinant human GIPC2 (1-315aa) purified from E. coli
特异性
亚型 IgG1,k
反应性 Human
克隆 AT1G10
Uniprot
浓度 1mg/ml
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB
别名 PDZ domain containing family, member 2, SEMCAP2.
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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