FSCN1 Antibody (Clone AT13D2)

抗人肌成束蛋白单克隆抗体

FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.
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基本信息

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货号 MA01258
规格 100 µL
宿主 Mouse
免疫原 Recombinant human FSCN1 (1-493aa) purified from E. coli
特异性
亚型 Mouse IgG2b, k
反应性 Human
克隆 Anti-human FSCN1 mAb, clone AT13D2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FSCN1 protein.
Uniprot
浓度 1 mg/ml
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB, ICC/IF, Flow cytometry
别名 Fascin, FAN1, HSN, SNL, Fascin
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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