CDK4 Antibody (Clone AT6D10)

抗人周期素依赖性激酶4

Cyclin-dependent kinase 4, also known as CDK4, belongs to the cyclin-dependent kinases (CDK) family. CDKs are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin up-regulates CDK4 activity, whereas binding to the CDK inhibitor p16 down-regulates CDK4 activity.
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基本信息

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货号 MA01166
规格 100 µL
宿主 Mouse
免疫原 Recombinant human CDK4 (1-303aa) purified from E. coli
特异性
亚型 IgG2a, k
反应性 Human
克隆 Anti-human CDK4 mAb, clone AT6D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CDK4 protein.
Uniprot
浓度 1 mg/ml
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB.
别名 Cyclin-dependent kinase 4, CMM3, PSK-J3.
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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