Anti-Mouse TGFB1 Polyclonal Antibody

TGFB1多克隆抗体

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.
价格: 2507.4元
  • Buy 5 for ¥2382.03 each and save 5%
  • Buy 21 for ¥2256.66 each and save 10%
  • Buy 31 for ¥2131.29 each and save 15%
  • Buy 51 for

基本信息

数据文档 查看数据文档
货号 PA01920
规格 100μl
宿主 Rabbit
免疫原 Recombinant Mouse Transforming growth factor beta-1 protein
特异性 Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage.
亚型 IgG
反应性 Mouse
克隆
Uniprot P01137
浓度 2 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC
别名 Cartilage-inducing factor,CED,Differentiation inhibiting factor,DPD1,LAP,Latency-associated peptide,Prepro transforming growth factor beta 1,TGF beta 1,TGF beta,TGF beta 1 protein,TGF-beta 1 protein,TGF-beta-1,TGF-beta-5,TGF-beta1,TGFB,Tgfb-1,tgfb1,TGFB1,TGFbeta,TGFbeta1,Transforming Growth Factor b1,Transforming Growth Factor beta 1,Transforming growth factor beta 1a,transforming growth factor beta-1,transforming growth factor,beta 1,Transforming Growth Factor-ß1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

©2024 武汉天正源生物科技有限公司版权所有. SiteMap