Anti-Human TREM1 Polyclonal Antibody

TREM1多克隆抗体

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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基本信息

数据文档 查看数据文档
货号 PA06287
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human TREM-1
特异性 Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
亚型 IgG
反应性 Human
克隆
Uniprot Q9NP99
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 CD354,OTTMUSP00000018206,TREM 1,TREM-1,TREM1,TREM1,Triggering receptor expressed on monocytes 1,Triggering receptor expressed on myeloid cells 1,Triggering receptor TREM 1,Triggering receptor TREM1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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