SULT1A1,also named as ST1A1,P-PST 1,ST1A3,Ts-PST,P-PST 1,STP and STP1,belongs to the sulfotransferase 1 family. It catalyzes the sulfate conjugation of catecholamines,phenolic drugs and neurotransmitters. SULT1A1 is also responsible for the sulfation and activation of minoxidil. It mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. SULT1A1 is one of two phenol sulfotransferases with thermostable enzyme activity.