Anti-Human SPARC Monoclonal Antibody

SPARC单克隆抗体

SPARC,also known as ON (Osteonectin) or BM-40 (Basement-membrane protein 40),is an extracellular glycoprotein with the calculated molecular mass of 35 kDa and the apparent molecular mass of 40-43 kDa and 50 kDa . SPARC belongs to a group of matricellular proteins defined as secreted components that do not contribute directly to the formation of structural elements but serve to modulate cell-matrix interactions and cellular functions . SPARC is expressed at high levels in bone tissue,is distributed widely in many other tissues and cell types,and is associated generally with tissues undergoing morphogenesis,remodeling and wound repair . It elicits changes in cell shape,inhibits cell-cycle progression,and influences the synthesis of extracellular matrix . Altered expression of SPARC has been reported in a variety of cancers,which include breast,ovarian,colorectal,and pancreatic cancer as well as melanoma and glioblastomas .
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基本信息

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货号 MA02560
规格 100μl
宿主 Mouse
免疫原 Fusion Protein of SPARC
特异性
亚型 IgG2a
反应性 Human
克隆 1A2C1
Uniprot P09486
浓度 None
推荐稀释度 WB 1:2000-1:10000
配方
应用范围 WB,ELISA
别名 AA517111,Basement membrane protein 40,Basement-membrane protein 40,BM 40,BM-40,BM40,Cysteine rich protein,hm:zeh0062,MGC128090,OI17,ON,Osteonectin,Secreted acidic cystein rich glycoprotein,Secreted protein acidic and cysteine rich,Secreted protein acidic and rich in cysteine,Secreted protein acidic cysteine rich (osteonectin),Secreted protein acidic cysteine rich,SPARC,SPRC,SPRC
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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