This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.SH2D2A (SH2 Domain Containing 2A) is a Protein Coding gene. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and Immune response Fc epsilon RI pathway. GO annotations related to this gene include SH3 domain binding and SH3/SH2 adaptor activity. An important paralog of this gene is SH2D7.