Anti-Human/Rat Survivin Monoclonal Antibody

Survivin单克隆抗体

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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基本信息

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货号 MA02601
规格 100μl
宿主 Mouse
免疫原 Recombinant Protein
特异性 Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines.
亚型 IgG
反应性 Human,Rat
克隆 4E2
Uniprot O15392
浓度 1mg/mL
推荐稀释度 WB 1:1000-2000, IHC 1:50-1:200
配方
应用范围 WB,IHC-p
别名 API4,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,Apoptosis inhibitor4,Baculoviral IAP repeat containing 5,Baculoviral IAP repeat containing protein 5,Baculoviral IAP repeat-containing protein 5,BIRC 5,BIRC5,BIRC5,EPR 1,IAP4,Survivin variant 3 alpha,SVV,TIAP
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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